Gemcitabine Hcl

Gemcitabine Hcl

Chemical Structure

Overview

Gemcitabine, sold under the brand name Gemzar, among others, is a chemotherapy medication used to treat cancers. It is used to treat testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. It is administered by intravenous infusion. It acts against neoplastic growth, and it inhibits the replication of Orthohepevirus A, the causative agent of Hepatitis E, through upregulation of interferon signaling.

Key Features

  • Molecular FormulaC9H11F2N3O4
  • Therapeutic Category Nucleoside Metabolic Inhibitor
  • API Technology High Potent
  • Dose Form Injectable

Use In

  • Breast cancer

    It is used as a second-line treatment in combination with paclitaxel for breast cancer that is metastatic or cannot be surgically removed.

  • Ovarian Cancer

    It is used as a second-line treatment in combination with carboplatin for ovarian cancer.

  • Pancreatic Cancer

    It is used as a first-line treatment alone for pancreatic cancer.

  • Bladder Cancer

    It is used in combination with cisplatin for advanced or metastatic bladder cancer.

  • Lung Cancer

    It is used in combination with cisplatin for advanced or metastatic non-small cell lung cancer.

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