Imatinib
Chemical Structure
Overview
Imatinib is an oral targeted therapy medication used to treat cancer. Imatinib is a small molecule inhibitor targeting multiple tyrosine kinases such as CSF1R, ABL, c-KIT, FLT3, and PDGFR-β.Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome–positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome.
Key Features
- Molecular Formula C29H31N7O
- Therapeutic Category Kinase Inhibitor
- API Technology High Potent
- Dose Form Tablet, oral solution
Use In
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Leukemia
Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies.
| Open Part | Close Part | IP | BP | USP | EP | IH |
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| Available | Under preparation |  |
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